J Neurophysiol. 2006 Feb;95(2):1176-84. Epub 2005 Nov 23.
Gebber GL, Orer HS, Barman SM.
So I read this paper, but I think I’m going to have to read
it a few more times with a lot of different highlighters if I’m really going to
understand it. I understand that they were trying to analyze rhythmic activity
among LTF and RVLM neurons in cats that correlates with SNA. This is not easy
since not every action potential correlates with bursts in SNA, and a neuron will
often NOT fire in a lot of places where a simple rhythm would dictate that it
should fire. However, using spike-triggered averaging, they analyzed the
interspike intervals of neurons to see how they would correlate with cardiac
SNA. They showed that even though some neurons might miss more than 10 bursts
before firing a second action potential, they still were able to construct
histograms that showed how the action potentials correlated with SNA, and what
phase of the cardiac cycle and SNA burst the neuron was most likely to fire at.
After that, the paper kind of got away from me. Although this is the exact kind
of stuff we’re trying to get in to, so I’ll be reading this a little more
closely and brushing up on my math skills so that I can understand all of this
a little better. -DH
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