Baroreceptor inputs modulate the bulbospinal neurons in the RVLM. To study these inputs, they used firing patterns to visualize them. Inputs that are started in low/high pressure baroreceptors express inhibition of the sympathoexcitatory neurons in the RVLM. This is done by either direct inhibition (IPSPs) or by disfacilitation. The purpose of the study was to investigate the barosensory properties of RVLM neurons using quantitative analysis between electrophys of the neurons and the barosensory activity in the AP. Time and frequency domain analysis were used to analyze the data. Frequency domain analysis is useful to look at signals containing multiple frequencies and it measures the coherence, which is a measure of the strength of coupling between two signals. The responses to electrical stimulation of the aortic nerve were examined in order to investigate the barosensory properties of the RVLM neurons. It was found that the potentials produced by aortic baroreceptor afferents were IPSPs. Also, a cardiac related rhythm was observed. Concluding the data showed that the neurons in the RVLM have baroreceptor input profiles that are different suc has excitation, excitation/inhibition, and inhibition.
By: Tsetse Fly
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